STRUCTURES OF SESQUITERPENE POLYOL ESTERS FROM CELASTRUS-STEPHANOTIIFOLIUS WITH POTENTIAL TUMOR-PROMOTION INHIBITORY ACTIVITY

被引：59

作者：

TAKAISHI, Y ^{[1
]}

OHSHIMA, S ^{[1
]}

NAKANO, K ^{[1
]}

TOMIMATSU, T ^{[1
]}

TOKUDA, H ^{[1
]}

NISHINO, H ^{[1
]}

IWASHIMA, A ^{[1
]}

机构：

[1] KYOTO PREFECTURAL UNIV MED,DEPT BIOCHEM,KYOTO 602,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 06期

关键词：

D O I：

10.1021/np50096a003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Esters of eight new ([1], [4-6],and [8-11]) and five known sesquiterpenenoid polyalcohols have been isolated from Celastrus stephanotiifolius. Their structures were established on the basis of chemical reactions and spectral analysis. The structural elucidation indicated that the structures of some related compounds should be revised. The isolated sesquiterpenes were observed to inhibit Epstein-Barr virus early antigen activation significantly at low doses.

引用

页码：815 / 824

页数：10

共 20 条

[1]

BRUNING R, 1978, PHYTOCHEMISTRY, V17, P1821, DOI 10.1016/S0031-9422(00)88719-1

[2]

GEUTAHAUN A, 1973, ECON BOT, V27, P353

[3] SESQUITERPENES FROM ORTHOSPHENIA-MEXICANA [J].

GONZALEZ, AG ;

GONZALEZ, CM ;

RAVELO, AG ;

FRAGA, BM ;

DOMINGUEZ, XA .

PHYTOCHEMISTRY, 1988, 27 (02) :473-477

[4] SESQUITERPENE ALKALOIDS FROM THE CELASTRACEAE [J].

GONZALEZ, AG ;

GONZALEZ, CM ;

BAZZOCCHI, IL ;

RAVELO, AG ;

LUIS, JG ;

DOMINGUEZ, XA .

PHYTOCHEMISTRY, 1987, 26 (07) :2133-2135

[5]

HARADA N, 1969, J AM CHEM SOC, V91, P4555

[6]

LIU J, 1989, CHINESE SCI BULL, V34, P1693

[7] SEARCH FOR POSSIBLE ANTITUMOR PROMOTERS BY INHIBITION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE-INDUCED EPSTEIN-BARR VIRUS-ACTIVATION - URSOLIC ACID AND OLEANOLIC ACID FROM AN ANTIINFLAMMATORY CHINESE MEDICINAL PLANT, GLECHOMA-HEDERACEAE L [J].

OHIGASHI, H ;

TAKAMURA, H ;

KOSHIMIZU, K ;

TOKUDA, H ;

ITO, Y .

CANCER LETTERS, 1986, 30 (02) :143-151

[8]

SHIZURI Y, 1973, TETRAHEDRON, V29, P1173

[9] CELORBICOL, ISOCELORBICOL, AND THEIR ESTERS - NEW SESQUITERPENOIDS FROM CELASTRUS-ORBICULATUS [J].

SMITH, CR ;

MILLER, RW ;

WEISLEDER, D ;

ROHWEDDER, WK ;

EICKMAN, N ;

CLARDY, J .

JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (20) :3264-3269

[10] GLYCOSIDES OF ERGOSTEROL DERIVATIVES FROM HERICUM-ERINACENS [J].

TAKAISHI, Y ;

UDA, M ;

OHASHI, T ;

NAKANO, K ;

MURAKAMI, K ;

TOMIMATSU, T .

PHYTOCHEMISTRY, 1991, 30 (12) :4117-4120

← 1 2 →