COEXISTENCE OF HETEROGENEOUS POPULATIONS OF TOXOPLASMA-GONDII PARASITES WITHIN PARASITOPHOROUS VACUOLES OF MURINE MACROPHAGES AS REVEALED BY A BRADYZOITE-SPECIFIC MONOCLONAL-ANTIBODY

被引：36

作者：

BOHNE, W ^{[1
]}

HEESEMANN, J ^{[1
]}

GROSS, U ^{[1
]}

机构：

[1] UNIV WURZBURG,INST HYG & MICROBIOL,JOSEF SCHNEIDER STR 2,D-97080 WURZBURG,GERMANY

来源：

PARASITOLOGY RESEARCH | 1993年 / 79卷 / 06期

关键词：

D O I：

10.1007/BF00931588

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The expression of bradyzoite-specific antigens (Bsa) of Toxoplasma gondii was studied in murine bone-marrow-derived macrophages that had previously been infected with tachyzoites. Growth conditions that allowed only restricted replication of Toxoplasma gondii resulted in heterogeneous populations; (1) Bsa-positive and Bsa-negative parasites could be observed within one parasitophorous vacuole (heterogeneous vacuole community), and (2) homogeneous Bsa-positive and homogeneous Bsa-negative vacuole communities coexisted within one macrophage host cell. These observations suggest that stage conversion does not seem to be a synchronous event for a vacuole community.

引用

页码：485 / 487

页数：3

共 7 条

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