MICROBIAL CONTAMINATION OF ANTIBIOTIC OPHTHALMIC OINTMENTS

被引：13

作者：

BOWMAN, FW

机构：

[1] National Center for Antibiotics and Insulin Analysis, Division of Pharmaceutical Sciences, Food and Drug Administration, Department of Health, Education, and Welfare, Washington, District of Columbia

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 02期

关键词：

Membrane filtration—sterility testing; Microbial contamination—ophthalmic antibiotic testing; Ophthalmic antibiotic ointments—sterility testing;

D O I：

10.1002/jps.2600580239

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A survey was conducted to determine the sterility of antibiotic ophthalmic ointments. One hundred fourteen batches of ointments from 16 manufacturers were tested by the membrane‐filtration procedure as described in the Antibiotic Regulations. Eight batches (7%) were found contaminated. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：277 / &

共 10 条

[1]

ANDERSON K F, 1963, Trans Ophthalmol Soc Aust, V23, P86

[2] STERILITY OF ANTIBIOTIC OPHTHALMIC OINTMENT [J].

BOWMAN, FW ;

HOLDOWSKY, S .

JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1959, 48 (02) :95-96

[3] IMPROVED VIABLE COUNTING METHOD FOR PETROLATUM-BASED OINTMENTS [J].

SOKOLSKI, WT ;

CHIDESTER, CG .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (01) :103-&

[4]

SOKOLSKI WT, 1961, ANTIBIOT CHEMOTHER, V11, P271

[5]

SOKOLSKI WT, UNPUBLISHED DATA

[6] A BACTERIOLOGICAL STUDY OF OPHTHALMIC OINTMENTS [J].

VANDERWYK, RW ;

GRANSTON, AE .

JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1958, 47 (03) :193-196

[7]

1968, CODE FEDERAL REG 130

[8]

1947, FEDERAL REGISTER, V12, P2223

[9]

1950, FEDERAL REGISTER, V15, P4976

[10]

1968, CODE FEDERAL REG 130, P239

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