CATECHOLAMINES AND DIAGNOSES IN CHILDREN

被引：37

作者：

ROGENESS, GA ^{[1
]}

JAVORS, MA ^{[1
]}

MAAS, JW ^{[1
]}

MACEDO, CA ^{[1
]}

机构：

[1] SW NEUROPSYCHIAT INST,SAN ANTONIO,TX

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1990年 / 29卷 / 02期

关键词：

catecholamines; conduct disorder; major depression; norepinephrine;

D O I：

10.1097/00004583-199003000-00012

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Theoretically, noradrenergic (NA) function may be lower in subjects with undersocialized conduct disorder (CDU) and higher in subjects with anxiety/depressive disorder. To test this hypothesis, diagnostic and 24-hour urine catecholamine measures were compared between subjects with plasma dopamine-β-hydroxylase (DβH) activities less than 6 μmoles/min/L (low DβH group) and greater than 15 μmoles/min/L (high DβH group). Several measures relating to norepinephrine metabolism were lower in the low DβH group, and the low DβH group had more diagnoses of CDU and fewer anxiety and depressive disorder diagnoses. Comparisons between clinical and biological measures within each of the DβH groups were also consistent with the hypothesized relationship between NA function, CDU, and anxiety/depressive disorder. © 1990, The American Academy of Child and Adolescent Psychiatry. All rights reserved.

引用

页码：234 / 241

页数：8

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