EFFECT OF THE LRF-ANTAGONIST [D-PGLU1, D-PHE2, D-TRP3,6]-LRF ON PREGNANCY IN THE RAT

被引：9

作者：

RIVIER, C

RIVIER, J

VALE, W

机构：

[1] Peptide Biology Laboratory The Salk Institute for Biological Studies La Jolla

来源：

CONTRACEPTION | 1979年 / 19卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0010-7824(79)80030-X

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The potent LRF-antagonist [D-pGlu1, D-Phe2, D-Trp3,6]-LRF (Antag.) has been examined for its effect in mated female rats. While 1.25 mg Antag. given b.i.d. for 7 days after mating prolongs pregnancy, the administration of 2.5 mg Antag. b.i.d. for the same period results in the complete absence of developing fetuses. © 1979 Geron-X, Inc.

引用

页码：185 / 190

页数：6

共 8 条

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[3] EFFECTS OF LUTEINIZING-HORMONE RELEASING HORMONE (LHRH) IN PREGNANT RATS .2. PRENIDATORY EFFECTS AND DELAYED PARTURITION
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[4] ANTI-FERTILITY EFFECTS OF AN ANALOG OF LUTEINIZING-HORMONE RELEASING HORMONE (LHRH) IN RATS
HUMPHREY, RR
WINDSOR, BL
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[5] LIN YC, 1976, 58TH END SOC M, P174
[6] RIVIER C, ENDOCRINOLOGY
[7] [D-PGLU1,D-PHE2,D-TRP3,6]-LRF - POTENT LUTEINIZING-HORMONE RELEASING FACTOR ANTAGONIST INVITRO AND INHIBITOR OF OVULATION IN RAT
RIVIER, JE
VALE, WW
[J]. LIFE SCIENCES, 1978, 23 (08) : 869 - 876
[8] REGULATORY PEPTIDES OF HYPOTHALAMUS
VALE, W
RIVIER, C
BROWN, M
[J]. ANNUAL REVIEW OF PHYSIOLOGY, 1977, 39 : 473 - 527

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