CORRELATION OF URINE PROTEIN CREATININE RATIO AND 24-HOUR URINARY PROTEIN EXCRETION IN NORMAL CATS AND CATS WITH SURGICALLY INDUCED CHRONIC-RENAL-FAILURE

被引：82

作者：

ADAMS, LG

POLZIN, DJ

OSBORNE, CA

OBRIEN, TD

机构：

[1] Departments of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota

来源：

JOURNAL OF VETERINARY INTERNAL MEDICINE | 1992年 / 6卷 / 01期

关键词：

D O I：

10.1111/j.1939-1676.1992.tb00983.x

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Urine protein/creatinine (UP/C) ratios and 24-hour urinary protein excretion were compared in clinically normal cats and cats with surgically induced chronic renal failure (CRF). Mean 24-hour urinary protein excretion in 30 clinically normal cats fed a 28% protein diet (dry weight basis) was 4.93 mg/kg/24-hour (SD = 1.34) with a range of 2.99 to 8.88. Mean UP/C ratio in these cats was 0.134 (SD = 0.037) with a range of 0.073 to 0.239. Mean 24-hour urinary protein excretion in CRF cats was 10.49 mg/kg/24-hour (SD = 11.28) with a range of 2.16 to 62.93. Mean UP/C ratio in the CRF cats was 0.359 (SD = 0.374) with a range of 0.061 to 1.916. Linear regression showed high correlation (R2 = 0.973, P < 0.001) between 24-hour urinary protein excretion and UP/C ratio in clinically normal cats and cats with surgically induced chronic renal failure. The regression equation for 24-hour urinary protein excretion versus UP/C ratio was: 24-hour urinary protein excretion = 29.39 (UP/C) + 0.18. Results of this study indicate that UP/C ratios are a valid estimate of 24-hour urinary protein excretion in clinically normal and CRF cats. Dietary protein intake significantly affected UP/C ratios in clinically normal cats and cats with surgically induced CRF. Therefore, the influence of dietary protein should be considered when interpreting UP/C ratios.

引用

页码：36 / 40

页数：5

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