COPULATION INCREASES DOPAMINE ACTIVITY IN THE MEDIAL PREOPTIC AREA OF MALE-RATS

被引：62

作者：

HULL, EM

EATON, RC

MOSES, J

LORRAIN, D

机构：

[1] Department of Psychology, State University of New York at Buffalo, Buffalo

来源：

LIFE SCIENCES | 1993年 / 52卷 / 11期

关键词：

D O I：

10.1016/0024-3205(93)90528-B

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Dopamine (DA) metabolites in microdialysates from the medial preoptic area (MPOA) of male rats increased during copulation. These increases were not observed during eating of a highly palatable food, or if the animal failed to copulate, or if the microdialysis probe was anterior or dorsal to the MPOA. The only two animals with measurable serotonin (5-HT) levels while the female was present were also the only two that either failed to copulate or copulated but failed to ejaculate. These data are consistent with previous evidence for a facilitative role of MPOA DA in the control of male sexual behavior; however, 5-HT activity in the MPOA may impair copulation.

引用

页码：935 / 940

页数：6

共 34 条

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[2]

[Anonymous], 1979, STEREOTAXIC ATLAS RA

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