ANODIC AMIDE OXIDATIONS - FUNDAMENTAL-STUDIES CONCERNING THE ANNULATION OF 6-MEMBERED AND 7-MEMBERED RINGS ONTO AMINES

被引：28

作者：

MOELLER, KD

ROTHFUS, SL

WONG, PL

机构：

[1] Department of Chemistry, Washington University, St. Louis

来源：

TETRAHEDRON | 1991年 / 47卷 / 4-5期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4020(01)87048-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The compatibility of olefinic and acetylenic nucleophiles with an electrochemically based annulation procedure for fusing six- and seven-membered rings onto amines has been examined. Both monosubstituted olefins and acetylenes were found to be good nucleophiles for annulating seven-membered rings onto amines. Disubstituted olefins and acetylenes appear to be good nucleophiles for completing the annulation of six-membered rings onto amines. In addition, the compatibility of several proline derivatives with the annulation procedure was examined.

引用

页码：583 / 592

页数：10

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