EVALUATION OF VAGINAL ANTIFUNGAL FORMULATIONS INVIVO

被引：11

作者：

MCRIPLEY, RJ

SCHWIND, RA

ERHARD, PJ

WHITNEY, RR

机构：

[1] Squibb Institute for Medical Research, Princeton, NJ

来源：

POSTGRADUATE MEDICAL JOURNAL | 1979年 / 55卷 / 647期

关键词：

D O I：

10.1136/pgmj.55.647.648

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal substances and for assessing the chemotherapeutic effectiveness of new antifungal agents and formulations before carrying out clinical studies. © 1979 The Fellowship of Postgraduate Medicine.

引用

页码：648 / 652

页数：5

共 5 条

[1] Mizuba S., 1974, Developments in Industrial Microbiology, V15, P338
[2] SYNERGISM OF POLYENE ANTIBIOTICS WITH 5-FLUOROCYTOSINE
POLAK, A
[J]. CHEMOTHERAPY, 1978, 24 (01) : 2 - 16
[3] SCHOLER H J, 1960, Pathol Microbiol (Basel), V23, P62, DOI 10.1159/000160970
[4] EXPERIMENTAL VAGINAL CANDIDIASIS IN MICE - ITS IMPLICATIONS FOR SUPERFICIAL CANDIDIASIS IN HUMANS
TASCHDJIAN, CL
REISS, F
KOZINN, PJ
[J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1960, 34 (02) : 89 - 94
[5] WILDFEUER A, 1974, ARZNEIMITTELFORSCH, V24, P937

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