CYCLIC GUANIDINES - SYNTHESIS OF 4,6,7,8-TETRAHYDRO-1H-IMIDAZO[1,2-A]PYRAZOLO[3,4-D]PYRIMIDIN-7-ONES AND 1,4,6,7,8,9-HEXAHYDROPYRAZOLO[3',4'-4,5]PYRIMIDO[2,1-C][1,2,4]TRIAZIN-7-ONES

被引：3

作者：

FERRONI, R ^{[1
]}

SIMONI, D ^{[1
]}

ORLANDINI, P ^{[1
]}

GUARNERI, M ^{[1
]}

BERTOLASI, V ^{[1
]}

FERRETTI, V ^{[1
]}

机构：

[1] UNIV FERRARA,CTR STRUTTURIST DIFFRATTOMETR,DIPARTIMENTO CHIM,I-44100 FERRARA,ITALY

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 04期

关键词：

D O I：

10.1002/jhet.5570270401

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of potential platelet aggregation inhibitors 4,6,7,8‐tetrahydroimidazo[1,2‐a]pyrazolo[3,4‐d]‐pyrimidin‐7‐ones and 1,4,6,7,8,9‐hexahydropyrazolo[3′,4′:4,5]pyrimido[2,1‐c] [1,2,4]triazin‐7‐ones derivatives is described starting from 4,6‐dichloropyrazolo[3,4‐d]pyrimidines. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：823 / 829

页数：7

共 12 条

[1]

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[2]

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[3]

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[4]

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[5]

FERRONI R, 1986, FARMACO, V41, P747

[6] POTENT NEW INHIBITOR OF PLATELET-AGGREGATION AND EXPERIMENTAL THROMBOSIS, ANAGRELIDE (BL-4162A) [J].

FLEMING, JS ;

BUYNISKI, JP .

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[7]

FRENZ BA, 1978, COMPUTING CRYSTALLOG, P41

[8]

ISCHIKAWA F, 1981, J MED CHEM, V24, P376

[9]

ISCHIKAWA F, 1985, J MED CHEM, V28, P1387

[10]

JOHNSON CK, 1976, ORNL5138 REP

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