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HIGH STEREOSELECTIVITY IN THE FORMATION OF THE INTER-RIBONUCLEOTIDIC PHOSPHOROTHIOATE BOND

被引：10
作者：
BATTISTINI, C
BRASCA, MG
FUSTINONI, S
机构：
[1] Farmitalia Carlo Erba (Erbamont Group), 35-20146 Milano, R. & D. Via dei Gracchi
来源：
NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期
关键词：
D O I：
10.1080/07328319108046582
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
2',5'-Phosphorothioates are synthesized with high S(p)-stereoselectivity by H-phosphonate method and subsequent thiooxidation.
引用
收藏
页码：723 / 725
页数：3
相关论文
共 4 条
[1]   SYNTHESIS OF P-THIOADENYLYL (2'-5') ADENOSINE AND P-THIOADENYLYL (2'-5')-P-THIOADENYLYL-(2'-5')-ADENOSINE [J].
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NUCLEOSIDES & NUCLEOTIDES, 1987, 6 (1-2) :513-516
[2]   PHOSPHOROTHIOATE ANALOGS OF 2',5'-OLIGOADENYLATE - ENZYMATICALLY SYNTHESIZED 2',5'-PHOSPHOROTHIOATE DIMER AND TRIMER - UNEQUIVOCAL STRUCTURAL ASSIGNMENT AND ACTIVATION OF 2',5'-OLIGOADENYLATE-DEPENDENT ENDORIBONUCLEASE [J].
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[3]   SYNTHESIS OF P-THIOADENYLYL-(2'-5')-ADENOSINE AND P-THIOADENYLYL-(2'-5')-P-THIOADENYLYL-(2'-5')-ADENOSINE [J].
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JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (13) :2314-2317
[4]  
SUHADOLNIK RJ, 1985, BIOCHEMISTRY-US, V24, P551
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