Rab GTPases in vesicular transport

被引：376

作者：

Zerial, Marino ^{[1
]}

Stenmark, Harald ^{[1
]}

机构：

[1] European Mol Biol Lab, D-6900 Heidelberg, Germany

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 04期

关键词：

D O I：

10.1016/0955-0674(93)90130-I

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Specificity and directionality are two features shared by the numerous steps of membrane transport that connect cellular organelles. By shuttling between specific membrane compartments and the cytoplasm, small GTPases of the Rab family appear to regulate membrane traffic in a cyclical manner. The restriction of certain Rab proteins to differentiated cell types supports a role for these GTPases in defining the specificity of membrane trafficking.

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收藏

页码：613 / 620

页数：8

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