DETERMINATION OF GAS-LIQUID PARTITION-COEFFICIENTS BY AUTOMATIC EQUILIBRIUM HEADSPACE - GAS-CHROMATOGRAPHY UTILIZING THE PHASE RATIO VARIATION METHOD

被引：151

作者：

ETTRE, LS ^{[1
]}

WELTER, C ^{[1
]}

KOLB, B ^{[1
]}

机构：

[1] BODENSEEWERK PERKIN ELMER & CO GMBH,W-7770 UBERLINGEN,GERMANY

来源：

CHROMATOGRAPHIA | 1993年 / 35卷 / 1-2期

关键词：

GAS CHROMATOGRAPHY; EQUILIBRIUM HEADSPACE SAMPLING; PARTITION COEFFICIENT DETERMINATION; THEORY OF CHROMATOGRAPHY;

D O I：

10.1007/BF02278560

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The new phase ratio variation method is described which represents a convenient way for the determination of gas-liquid partition coefficients for practical purposes, utilizing equilibrium headspace - gas chromatography (EHS-GC). This method is based on the relationship between reciprocal peak area and the phase ratio in the vial containing the sample solution; it involves regression analysis of the EHS-GC measurements of a number of sample vials containing the same sample solution but with a wide variation of phase ratios. Examples are given for both aqueous systems and systems consisting of a stationary (liquid) phase used as the solvent; comparison of the measured values with results obtained by other methods shows satisfactory agreement. A critical discussion of the conditions influencing the accuracy of the analytical results is given.

引用

页码：73 / 84

页数：12

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