SEQUENCING OF A CDNA-ENCODING THE HUMAN FAST-TWITCH SKELETAL-MUSCLE ISOFORM OF TROPONIN-I

被引：22

作者：

ZHU, L

PEREZALVARADO, G

WADE, R

机构：

[1] UNIV MARYLAND,SCH MED,DEPT BIOL CHEM,BALTIMORE,MD 21201

[2] UNIV MARYLAND,SCH MED,CELL & MOLEC BIOL PROGRAM,BALTIMORE,MD 21201

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1994年 / 1217卷 / 03期

基金：

美国国家科学基金会;

关键词：

TROPONIN; CONTRACTILE PROTEIN; CDNA SEQUENCE;

D O I：

10.1016/0167-4781(94)90297-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA encoding the human fast-twitch skeletal muscle isoform of troponin I (TnI(fast)) has been sequenced. This cDNA is 701 base pairs in length, and encodes a protein of 182 amino acids. TnI(fast) is the last of the three known human TnI isoforms to be sequenced. Comparison of the deduced human TnI(fast) protein sequence with a variety of troponin I isoforms from other species has revealed a high degree of cross-species sequence conservation between TnI(fast) proteins.

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页码：338 / 340

页数：3

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