CLONING AND SEQUENCE OF A CHICKEN ALPHA-N-ACETYLGALACTOSAMINIDASE GENE

被引：13

作者：

DAVIS, MO

HATA, DJ

SMITH, D

WALKER, JC

机构：

[1] UNIV MISSOURI,DEPT PATHOL,M263 MED SCI BLDG,1 HOSP DR,COLUMBIA,MO 65212

[2] UNIV MISSOURI,DIV BIOL SCI,COLUMBIA,MO 65211

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1216卷 / 02期

关键词：

EXOGLYCOSIDASE; ABO BLOOD GROUP SYSTEM; CDNA CLONING; GENE SEQUENCING; (CHICKEN);

D O I：

10.1016/0167-4781(93)90158-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cDNA clone encoding the mature polypeptide for the chicken liver alpha-N-acetylgalactosaminidase enzyme was isolated by screening a cDNA library with a synthetic sequence derived from the human alpha-N-acetylgalactosaminidase gene. The deduced amino acid sequence of the chicken liver clone was identical to the amino-terminal and cyanogen bromide derived peptide sequences obtained from the purified enzyme. The chicken enzyme has 75% identity with the human alpha-N-acetylgalactosaminidase and 56-33% identity with alpha-galactosidases from several sources.

引用

页码：296 / 298

页数：3

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