The parameters of density-dependent effective interaction suggested by Bethe are determined from restricted Hartree-Fock calculations in 4He, 16O, 40Ca and infinite nuclear matter. The parameters of an equivalent momentum-dependent interaction are also studied. It is shown that the contributions of the proposed density-dependent interaction to the binding energy of nuclear matter closely resemble those of the Reid potential. The distribution of neutron and proton densities in 40Ca, 120Sn and 208Pb is studied with this interaction by a variational method using local density approximation. The calculated binding energies, radii, central densities and surface thickness are in good agreement with the experimental data. © 1969.