SYNTHESIS AND ANTI-VIRAL AND ENZYMATIC STUDIES OF CERTAIN 3-DEAZAGUANINES AND THEIR IMIDAZOLECARBOXAMIDE PRECURSORS

被引：31

作者：

COOK, PD ^{[1
]}

ALLEN, LB ^{[1
]}

STREETER, DG ^{[1
]}

HUFFMAN, JH ^{[1
]}

SIDWELL, RW ^{[1
]}

ROBINS, RK ^{[1
]}

机构：

[1] ICN PHARMACEUT INC,NUCL ACID RES INST,IRVINE,CA 92715

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1978年 / 21卷 / 12期

关键词：

D O I：

10.1021/jm00210a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1212 / 1218

页数：7

共 28 条

[1] ANTIVIRAL ACTIVITY OF 3-DEAZAGUANINE, 3-DEAZAGUANOSINE, AND 3-DEAZAGUANYLIC ACID
ALLEN, LB
HUFFMAN, JH
COOK, PD
MEYER, RB
ROBINS, RK
SIDWELL, RW
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 12 (01) : 114 - 119
[2] SYNTHESIS OF 7-BETA-D-RIBOFURANOSIDES AND 9-BETA-D-RIBOFURANOSIDES OF 3-DEAZA-6-THIOGUANINE AND 3-DEAZA-2,6-DIAMINOPURINE BY A NOVEL RING-CLOSURE OF 4(5)-CYANO-5(4)-CYANOMETHYLIMIDAZOLE-BETA-D-RIBOFURANOSIDES
COOK, PD
ROBINS, RK
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (02) : 289 - 293
[3] NEW CLASS OF POTENT GUANINE ANTIMETABOLITES - SYNTHESIS OF 3-DEAZAGUANINE, 3-DEAZAGUANOSINE, AND 3-DEAZAGUANYLIC ACID BY A NOVEL RING-CLOSURE OF IMIDAZOLE PRECURSORS
COOK, PD
ROUSSEAU, RJ
MIAN, AM
MEYER, RB
DEA, P
IVANOVICS, G
STREETER, DG
WITKOWSKI, JT
STOUT, MG
SIMON, LN
SIDWELL, RW
ROBINS, RK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (10) : 2916 - 2917
[4] SYNTHESIS OF 3-DEAZAGUANINE, 3-DEAZAGUANOSINE, AND 3-DEAZAGUANYLIC ACID BY A NOVEL RING-CLOSURE OF IMIDAZOLE PRECURSORS
COOK, PD
ROUSSEAU, RJ
MIAN, AM
DEA, P
MEYER, RB
ROBINS, RK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (06) : 1492 - 1498
[5] FLAKS JG, 1957, J BIOL CHEM, V229, P603
[6] HARTMAN SC, 1970, METABOLIC PATHWAYS, V4, P1
[7] EFFECTS OF NUCLEOSIDE ANALOGS ON PURINE NUCLEOTIDE-METABOLISM
HENDERSON, JF
SMITH, CM
SNYDER, FF
ZOMBOR, G
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1975, 255 (AUG8) : 489 - 500
[8] KHWAJA TA, 1976, P AM ASSOC CANC RES, V17, P200
[9] KHWAJA TA, 1975, P AM ASSOC CANC RES, V16, P162
[10] LUKENS LN, 1963, METHOD ENZYMOL, V6, P696

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