CHROMOSOME-1 ABNORMALITIES IN RELAPSE AND TERMINAL STAGES IN CHILDHOOD LEUKEMIA

被引：14

作者：

MORSE, H

HAYS, T

ROSE, B

ROBINSON, A

机构：

[1] Departments of Pathology, Children's Hospital, Denver, Colorado

[2] Department of Biochemistry, Biophysics and Genetics and Department of Pediatrics, University of Colorado Medical School, Denver, Colorado

[3] National Jewish Hospital and Research Center, Denver, Colorado

来源：

MEDICAL AND PEDIATRIC ONCOLOGY | 1979年 / 7卷 / 01期

关键词：

chromosome aberrations; cytogenetic study; terminal stages;

D O I：

10.1002/mpo.2950070103

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Seven of 114 children with leukemia were shown to have abnormalities of chromosome 1. These included trisomy of parts of chromosome 1 as well as translocations of chromosome 1 to other chromosomes. The abnormalities were found during a relapse or terminal stage, after which the patient was refractory to therapy in all cases. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：9 / 16

页数：8

共 15 条

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