INTRACTABLE EPIDERMOLYSIS-BULLOSA ACQUISITA - EFFICACY OF CYCLOSPORINE-A

被引：21

作者：

MERLE, C ^{[1
]}

BLANC, D ^{[1
]}

ZULTAK, M ^{[1
]}

VANLANDUYT, H ^{[1
]}

DROBACHEFF, C ^{[1
]}

LAURENT, R ^{[1
]}

机构：

[1] HOP ST JACQUES, DEPT DERMATOL, F-25030 BESANCON, FRANCE

来源：

DERMATOLOGICA | 1990年 / 181卷 / 01期

关键词：

ciclosporin; Epidermolysis bullosa acquisita;

D O I：

10.1159/000247859

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report the case of a 66-year-old man who presented with a spontaneous blistering involving both skin and mucous membranes, diagnosed as an inflammatory form of epidermolysis bullosa acquisita. During a 5-year course, the condition failed to respond to various therapies. Finally, only ciclosporin, together with a low dose regimen of prednisone, achieved a dramatic improvement with a total clearing within 6 months, persisting 1 1/2 years after discontinuation. Such results prompt us to propose such an association as a primary therapeutic scheme in an otherwise barely tractable disease.

引用

页码：44 / 47

页数：4

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