URINARY AMMONIA PLUS URINARY UREA NITROGEN AS AN ESTIMATE OF TOTAL URINARY NITROGEN IN PATIENTS RECEIVING PARENTERAL-NUTRITION SUPPORT

被引:15
作者
BURGE, JC
CHOBAN, P
MCKNIGHT, T
KYLER, MK
FLANCBAUM, L
机构
[1] OHIO STATE UNIV HOSP,DEPT SURG,DOAN N737,410 W 10TH AVE,COLUMBUS,OH 43210
[2] OHIO STATE UNIV,SCH ALLIED MED PROFESS,DIV MED DIETET,COLUMBUS,OH 43210
[3] OHIO STATE UNIV,DEPT SURG,COLUMBUS,OH 43210
[4] OHIO STATE UNIV HOSP,NUTR SUPPORT SERV,COLUMBUS,OH 43210
关键词
D O I
10.1177/0148607193017006529
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Nitrogen balance has historically been estimated by using urinary urea nitrogen (UUN) multiplied by a factor of 1.25 to account for nonurea nitrogen present in the urine. Recently, the reliability of UUN as an estimate of nitrogen losses has been questioned and the use of total urinary nitrogen (TUN) has been proposed as a more accurate measure of urinary nitrogen losses. However, analysis of TUN losses is not readily available in many hospital laboratories. Because ammonia is the major fluctuating component of urinary nonurea nitrogen and equipment to measure urinary ammonia is available in most hospitals, this study was undertaken to determine whether urinary ammonia plus UUN provides a clinically useful approximation of TUN. Twenty-four-hour urine samples acidified with boric acid during collection from 20 patients (a total of 42 samples) receiving total parenteral nutrition were analyzed for UUN, ammonia, and TUN. The UUN values ranged from 4.9 to 42.4 g/24 h. The mean difference between TUN and UUN was 1.99 +/- 0.27 g/24 h. The mean difference between TUN and UUN plus ammonia was 0.78 +/- 0.27 g/24 h. Thus, UUN alone accounted for 90% and the combination of UUN plus urinary ammonia accounted for 96% of TUN. These data suggest that UUN plus ammonia does provide a greater level of reliability as an estimate of TUN than UUN alone.
引用
收藏
页码:529 / 531
页数:3
相关论文
共 11 条
[1]  
ALLISON JB, 1964, MAMMALIAN PROTEIN ME, V1, P483
[2]  
BELL SJ, 1985, J AM DIET ASSOC, V85, P1100
[3]  
Blackburn G L, 1977, JPEN J Parenter Enteral Nutr, V1, P11, DOI 10.1177/014860717700100111
[4]  
Bradstreet R., 1965, KJELDAHL METHOD ORGA, DOI 10.1016/C2013-0-12545-7
[5]  
BUTTERWORTH CE, 1974, NUTR TODAY, V1, P4
[6]   ASSESSMENT OF AN AUTOMATED CHEMI-LUMINESCENCE NITROGEN ANALYZER FOR ROUTINE USE IN CLINICAL NUTRITION [J].
GRIMBLE, GK ;
WEST, MFE ;
ACUTI, ABC ;
REES, RG ;
HUNJAN, MK ;
WEBSTER, JD ;
FROST, PG ;
SILK, DBA .
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1988, 12 (01) :100-106
[7]  
HORAK E, 1972, ANN CLIN LAB SCI, V2, P6
[8]   URINARY UREA NITROGEN - TOO INSENSITIVE FOR CALCULATING NITROGEN-BALANCE STUDIES IN SURGICAL CLINICAL NUTRITION [J].
KONSTANTINIDES, FN ;
KONSTANTINIDES, NN ;
LI, JC ;
MYAYA, ME ;
CERRA, FB .
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1991, 15 (02) :189-193
[9]  
LODER P, 1989, CRIT CARE MED, V1, P309
[10]   DETERMINATION OF OPTIMAL HYPERALIMENTATION INFUSION RATE [J].
RUTTEN, P ;
BLACKBURN, GL ;
FLATT, JP ;
HALLOWELL, E ;
COCHRAN, D .
JOURNAL OF SURGICAL RESEARCH, 1975, 18 (05) :477-483