CONTROL OF THE INITIATION OF DNA-REPLICATION IN ESCHERICHIA-COLI .1. NEGATIVE CONTROL OF INITIATION

被引：64

作者：

TIPPESCHINDLER, R ^{[1
]}

ZAHN, G ^{[1
]}

MESSER, W ^{[1
]}

机构：

[1] MAX PLANCK INST MOLEC GENET,IHNESTR 63-73,D-1000 BERLIN 33,FED REP GER

来源：

MOLECULAR & GENERAL GENETICS | 1979年 / 168卷 / 02期

关键词：

D O I：

10.1007/BF00431444

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A transient stimulation of the initiation of DNA replication during inhibition of protein synthesis has been demonstrated in dnaA5 and dnaA46 mutants. This suggests the existence of a negatively acting control protein (not the dnaA product) which decays rapidly or is removed during a block in protein synthesis. The stimulation of initiation is dependent on a previous accumulation of initiation specific proteins, which suggests that in addition to the negative control other control mechanisms are effective. © 1979 Springer-Verlag.

引用

页码：185 / 195

页数：11

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