TERMINAL AMINO ACID RESIDUES OF OVINE INTERSTITIAL CELL-STIMULATING HORMONE AND ITS SUBUNITS

被引：12

作者：

SAMY, TSA

PAPKOFF, H

LI, CH

机构：

[1] Hormone Research Laboratory, School of Medicine, University of California, San Francisco

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1969年 / 130卷 / 1-2期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0003-9861(69)90086-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ovine ICSH and its subunits, C I and C II, have been analyzed for their NH2- and COOH-terminal groups. The phenylisothiocyanate reaction has shown proline to be at the N-terminus of ICSH, C I, and C II, a fact not previously known. Studies with carboxypeptidase A show that the native ICSH has two C-terminal amino acids; namely, serine and leucine. Subunit C I has serine at its COOH-terminus with the sequence ..... Tyr.Tyr.Ser.OH; subunit C II terminates with a leucine residue with the sequence ..... Cys.Ile.Leu.OH. © 1969.

引用

页码：674 / &

共 22 条

[1] ON THE HYDRAZINOLYSIS OF PROTEINS AND PEPTIDES - A METHOD FOR THE CHARACTERIZATION OF CARBOXYL-TERMINAL AMINO ACIDS IN PROTEINS [J].