INSULIN-LIKE GROWTH FACTOR-I IN PATIENTS WITH HYPOGLYCEMIA

被引：6

作者：

LABIB, M ^{[1
]}

TEALE, D ^{[1
]}

MARKS, V ^{[1
]}

机构：

[1] ST LUKES HOSP,DEPT CLIN BIOCHEM & CLIN NUTR,GUILDFORD GU1 3NT,SURREY,ENGLAND

来源：

ANNALS OF CLINICAL BIOCHEMISTRY | 1990年 / 27卷

关键词：

insulin; insulinoma; proinsulin;

D O I：

10.1177/000456329002700203

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Plasma insulin-like growth factor 1 (IGF-1) concentrations were measured in a group of patients with hypoglycaemia due to endogenous hyperinsulinism, and compared with those in a group of patients matched for age and sex with hypoglycaemia and appropriately suppressed insulin levels. Insulin-like growth factor I concentrations were significantly higher in the hyperinsulinaemic hypoglycaemic group than in either the hypoinsulinaemic hypoglycaemia group or a group of euglycaemic control subjects. These data provide further evidence that insulin promotes IGF-1 production and release from the liver. © 1990, Association for Clinical Biochemistry. All rights reserved.

引用

页码：107 / 109

页数：3

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