SYNTHESIS OF 6-O-(2-AMINOETHYL)-D,L-MYO-INOSITOL-1,2-CYCLIC PHOSPHATE - A MODEL OF A PUTATIVE INSULIN 2ND MESSENGER

被引：18

作者：

COBB, JE

JOHNSON, MR

机构：

来源：

TETRAHEDRON | 1991年 / 47卷 / 01期

关键词：

D O I：

10.1016/0040-4020(91)80004-L

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the titled compound 2 is described. This material was synthesized to aid in the structural elucidation of a putative insulin second messenger. It was designed to be a potential insulinomimetic as well. © 1991.

引用

页码：21 / 30

页数：10

共 23 条

[1] A SYNTHESIS OF 1D-MYO-INSITOL AND 1L-MYO-INOSITOL 1,3,4,5-TETRAPHOSPHATE [J].

BAUDIN, G ;

GLANZER, BI ;

SWAMINATHAN, KS ;

VASELLA, A .

HELVETICA CHIMICA ACTA, 1988, 71 (05) :1367-1378

[2] GLYCOSYL-INOSITOL DERIVATIVES .2. SYNTHESIS OF 2-AMINO-2-DEOXY-D-GALACTOSYL-ALPHA-1,3-D-CHIRO-INOSITOL [J].

BERLIN, WK ;

WANG, SN ;

SHEN, TY .

TETRAHEDRON LETTERS, 1990, 31 (08) :1109-1112

[3] SYNTHESIS OF MYOINOSITOL 1,3,4,5-TETRAPHOSPHATE AND MYOINOSITOL 1,3-BISPHOSPHATE [J].

BILLINGTON, DC ;

BAKER, R .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (13) :1011-1013

[4] SYNTHESIS OF MYOINOSITOL 1-PHOSPHATE AND 4-PHOSPHATE, AND OF THEIR INDIVIDUAL ENANTIOMERS [J].

BILLINGTON, DC ;

BAKER, R ;

KULAGOWSKI, JJ ;

MAWER, IM .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (04) :314-316

[5]

CERDAN S, 1986, J BIOL CHEM, V261, P4676

[6] EPIDERMAL GROWTH-FACTOR AND INSULIN-LIKE GROWTH FACTOR-I STIMULATE THE HYDROLYSIS OF THE INSULIN-SENSITIVE PHOSPHATIDYLINOSITOL-GLYCAN IN BC3H-1 MYOCYTES [J].

FARESE, RV ;

NAIR, GP ;

STANDAERT, ML ;

COOPER, DR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 156 (03) :1346-1352

[7]

FERGUSON MAJ, 1985, J BIOL CHEM, V260, P4547

[8] GLYCOSYL-PHOSPHATIDYLINOSITOL MOIETY THAT ANCHORS TRYPANOSOMA-BRUCEI VARIANT SURFACE GLYCOPROTEIN TO THE MEMBRANE [J].

FERGUSON, MAJ ;

HOMANS, SW ;

DWEK, RA ;

RADEMACHER, TW .

SCIENCE, 1988, 239 (4841) :753-759

[9] SYNTHESIS OF SOME MONO-O-BENZYL-MYO-INOSITOL AND PENTA-O-METHYL-MYO-INOSITOL [J].

GAREGG, PJ ;

IVERSEN, T ;

JOHANSSON, R ;

LINDBERG, B .

CARBOHYDRATE RESEARCH, 1984, 130 (JUL) :322-326

[10] COMPLETE STRUCTURE OF THE GLYCOSYL PHOSPHATIDYLINOSITOL MEMBRANE ANCHOR OF RAT-BRAIN THY-1 GLYCOPROTEIN [J].

HOMANS, SW ;

FERGUSON, MAJ ;

DWEK, RA ;

RADEMACHER, TW ;

ANAND, R ;

WILLIAMS, AF .

NATURE, 1988, 333 (6170) :269-272

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