HERPES-SIMPLEX VIRUS INDUCES FOS EXPRESSION IN RAT BRAIN-STEM NEURONS

被引：9

作者：

GIEROBA, ZJ

ZHU, BS

BLESSING, WW

WESSELINGH, SL

机构：

[1] FLINDERS UNIV S AUSTRALIA,CTR NEUROSCI,DEPT MED,BEDFORD PK,SA 5042,AUSTRALIA

[2] FLINDERS UNIV S AUSTRALIA,CTR NEUROSCI,DEPT MICROBIOL & INFECT DIS,BEDFORD PK,SA 5042,AUSTRALIA

来源：

BRAIN RESEARCH | 1995年 / 675卷 / 1-2期

关键词：

HERPES SIMPLEX VIRUS; FOS; VAGUS NERVE; MEDULLA OBLONGATA;

D O I：

10.1016/0006-8993(95)00016-J

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.

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页码：329 / 332

页数：4

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