ALKALINE DEGRADATION OF DEOXYRIBONUCLEIC ACID DERIVATIVES

被引:44
作者
JONES, AS
MIAN, AM
WALKER, RT
机构
来源
JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1968年 / 16期
关键词
D O I
10.1039/j39680002042
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Alkaline degradation of apurinic acid and apyrimidinic acid gave, in addition to oligonucleotides and inorganic phosphate, appreciable amounts of 2-oxocyclopent-1-enyl phosphate, identical with a sample obtained by the phosphorylation of cyclopentane-1,2-dione. A mechanism for the alkaline degradation of these deoxyribonucleic acid derivatives consistent with these results and those of other workers is proposed.
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页码:2042 / &
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