LAMELLAR MEMBRANE ENCIRCLED VIRUSES IN ERYTHROCYTES OF RANA PIPIENS

In the erythrocytes of adult leopard frogs, viral particles were identified by the electron microscope. These viruses were identified in the inclusion seen previously by conventional blood staining methods in the light microscope. The viruses, whose nucleoid probably contained DNA, were usually polygonal, primarily hexagonal, rarely circular and consisted of two electron lucent zones enclosing an electron dense zone between them. In relation to the cytoplasm, the viruses exhibited an unusual lamellar phenomenon composed of stacked membranes. © 1969 Academic Press, Inc.