SYNTHESIS OF EPIMERIC 15-HYDROXYESTRIOLS NEW AND POTENTIAL METABOLITES OF ESTRADIOL

被引:18
作者
FISHMAN, J
GUZIK, H
机构
[1] Institute for Steroid Research, Montefiore Hospital and Medical Center, New York
关键词
D O I
10.1021/jo01272a023
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of estra-1,3,5(10)-triene-3,15α, 16α, 17β-tetrol, a new metabolite of estradiol, and of estra-1,3,5(10)- triene-3,15β,16α,17β-tetrol, a potential metabolite, are described. The nuclear magnetic resonance spectra of the corresponding tetraacetates which were instrumental in assigning the correct structures are discussed. © 1968, American Chemical Society. All rights reserved.
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页码:3133 / &
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