PLATELET-AGGREGATION IN EXPERIMENTAL SPINAL-CORD INJURY - ULTRASTRUCTURAL OBSERVATIONS

被引：50

作者：

GOODMAN, JH

BINGHAM, WG

HUNT, WE

机构：

[1] Division of Neurological Surgery, College of Medicine, Ohio State University, Columbus

来源：

ARCHIVES OF NEUROLOGY | 1979年 / 36卷 / 04期

关键词：

D O I：

10.1001/archneur.1979.00500400051006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Endothelial alterations occur as early as 1½ minutes following impact injury to the primate spinal cord. Separation of the endothelial junctions and exposure of microvascular basal lamina result in platelet adhesion and aggregations that cover defects in the vessel wall and may progress to complete vascular occlusion. This occurs during the first six hours following injury. Platelets also adhere to the surface of damaged endothelium. Hemostasis resulting from platelet thrombus formation is responsible in part for decreased blood flow in the central gray matter following spinal cord trauma. © 1979, American Medical Association. All rights reserved.

引用

页码：197 / 201

页数：5

共 17 条

[1] INHIBITION OF PLASMIN, TRYPSIN AND THE STREPTOKINASE-ACTIVATED FIBRINOLYTIC SYSTEM BY EPSILON-AMINOCAPROIC ACID [J].