POLYCYSTIC OVARIAN DISEASE

被引：40

作者：

BARBIERI, RL

机构：

来源：

ANNUAL REVIEW OF MEDICINE | 1991年 / 42卷

关键词：

INSULIN RESISTANCE; INSULIN RECEPTOR GENE; HAIR-AN SYNDROME; ACANTHOSIS NIGRICANS; ANDROGENS;

D O I：

10.1146/annurev.med.42.1.199

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Polycystic ovarian disease (PCOD) is a common endocrinopathy in women of reproductive age. Its molecular causes remain to be fully defined. Hyperinsulinemia and hyperandrogenism are positively correlated, which suggests that insulin resistance may be involved in the pathogenesis of PCOD. Point mutations in the insulin receptor gene that cause insulin resistance appear to be associated with the PCOD phenotype.

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页码：199 / 204

页数：6

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