PHOSPHATIDYLINOSITOL MEMBRANE ANCHORS AND T-CELL ACTIVATION

被引：291

作者：

ROBINSON, PJ

机构：

[1] Transplantation Biology Section, Clinical Research Centre, Harrow, Middlesex HA 1 3 UJ, Watford Road

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 01期

关键词：

D O I：

10.1016/0167-5699(91)90110-F

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A number of lymphocyte proteins are attached to the cell membrane via glycophosphatidylinositol-anchoring domains. Antibodies specific for several of these proteins are potent mitogens for T cells. In this article, Peter Robinson reviews recent evidence for the involvement of these membrane anchors in cell signalling events and discusses their possible significance in providing antigen-independent costimulatory signals to lymphoid cells.

引用

页码：35 / 41

页数：7

共 55 条

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