CALCITONIN-PRODUCING INSULINOMA - CLINICAL, IMMUNOCYTOCHEMICAL AND CYTOGENETICAL STUDY

被引：17

作者：

BUGALHO, MJGM

ROQUE, L

SOBRINHO, LG

HOOG, A

NUNES, JFM

ALMEIDA, JMM

LEITAO, CN

SANTOS, JR

PEREIRA, MC

SANTOS, MA

SOARES, J

机构：

[1] PORTUGUESE CANC INST,DEPT PATHOL,LISBON,PORTUGAL

[2] PORTUGUESE CANC INST,DEPT SURG,LISBON,PORTUGAL

[3] PORTUGUESE CANC INST,DEPT GASTROENTEROL,LISBON,PORTUGAL

[4] KAROLINSKA INST,DEPT PATHOL,S-10401 STOCKHOLM,SWEDEN

来源：

CLINICAL ENDOCRINOLOGY | 1994年 / 41卷 / 02期

关键词：

D O I：

10.1111/j.1365-2265.1994.tb02539.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The case of a patient with a large goitre associated with hypercalcitoninaemia and fasting hypoglycaemia is reported. Pentagastrin (PG) test was negative. Repeated measurements of fasting glycaemia, insulin and C peptide established the diagnosis of insulinoma. After localization by endoscopic ultrasonography, a distal pancreatectomy was performed and a small insulinoma was recovered. Glycaemia and calcitonin (CT) became normal. The tumour cells displayed a strong immunoreactivity for insulin and CT. Cytogenetical evaluation of the tumour revealed a translocation t(1;9) (p13;p22).

引用

页码：257 / 260

页数：4

共 17 条

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