FREQUENCY ENCODING IN EXCITABLE SYSTEMS WITH APPLICATIONS TO CALCIUM OSCILLATIONS

被引：56

作者：

TANG, YH ^{[1
]}

OTHMER, HG ^{[1
]}

机构：

[1] UNIV UTAH, DEPT MATH, SALT LAKE CITY, UT 84112 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 17期

关键词：

CALCIUM CHANNELS; MATHEMATICAL MODEL; INOSITOL 1,4,5-TRISPHOSPHATE;

D O I：

10.1073/pnas.92.17.7869

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A number of excitable cell types respond to a constant hormonal stimulus with a periodic oscillation in intracellular calcium. The frequency of oscillation is often proportional to the hormonal stimulus, and one says that the stimulus is frequency encoded. Here we develop a theory of frequency encoding in excitable systems and apply it to intracellular calcium oscillations that result from increases in the intracellular level of inositol 1,4,5-trisphosphate.

引用

页码：7869 / 7873

页数：5

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