PILOT STUDY OF FACTORS ASSOCIATED WITH EXACERBATIONS IN CHRONIC BRONCHITIS

被引：64

作者：

FISHER, M

AKHTAR, AJ

CALDER, MA

MOFFAT, MAJ

STEWART, SM

ZEALLEY, H

CROFTON, JW

机构：

[1] Department of Respiratory Diseases, University of Edinburgh

[2] Department of Respiratory Diseases, University of Edinburgh, University Department of Geriatrics, Stobhill General Hospital, Glasgow

[3] City Hospital, Edinburgh

[4] City Hospital, Department of Bacteriology, University of Aberdeen, Edinburgh

[5] Department of Bacteriology, University of Edinburgh

[6] Wellcome Laboratory, City Hospital, Edinburgh

来源：

BMJ-BRITISH MEDICAL JOURNAL | 1969年 / 4卷 / 5677期

基金：

英国医学研究理事会; 英国惠康基金;

关键词：

D O I：

10.1136/bmj.4.5677.187

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The factors associated with exacerbations of chronic bronchitis were investigated in a pilot study of 23 male patients over a period of 29 months. There were 63 exacerbations—56 were fully investigated and in seven only serological studies were possible. Evidence of the presence of an infective agent was sought in the early stages of the exacerbations and during relative quiescence. Significantly more potential pathogens, both bacterial (pneumococci and Haemophilus influenzae) and viral and mycoplasmal, were found during exacerbations than in quiescent periods. It was not possible to demonstrate that atmospheric pollution or low temperature influenced exacerbations, but the data are insufficient to exclude a small effect. It is emphasized that the value of future work on these lines would be increased if agreement could be reached on the definition of an exacerbation. © 1969, British Medical Journal Publishing Group. All rights reserved.

引用

页码：187 / +

页数：1

共 26 条

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