DIFFERENTIAL CELLULAR-LOCALIZATION OF ENZYMES OF L-ARGININE METABOLISM IN THE RAT-BRAIN

被引：52

作者：

NAKAMURA, H

SAHEKI, T

NAKAGAWA, S

机构：

[1] KAGOSHIMA UNIV,FAC MED,DEPT ANAT,1208-1 USUKI CHO,KAGOSHIMA 890,JAPAN

[2] KAGOSHIMA UNIV,FAC MED,DEPT BIOCHEM,KAGOSHIMA 890,JAPAN

来源：

BRAIN RESEARCH | 1990年 / 530卷 / 01期

关键词：

Arginase; Argininosuccinate lyase; Argininosuccinate synthetase; Cerebellar cortex; Immunohistochemistry; Motor nucleus; Olfactory bulb; Urea cycle;

D O I：

10.1016/0006-8993(90)90664-W

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Polyclonal rabbit antisera specific to argininosuccinate synthetase (ASS), argininosuccinate lyase and arginase revealed that these enzymes of l-arginine metabolism are generally localized in different cells of the rat brain. In the main olfactory bulb and the cerebellar cortex the three immunoreactivities were localized in different cells: in the somatic motor nuclei ASS-like immunoreactivity was localized in incoming fibers, and the other two enzymes were found in the motor neurons. The results suggest that l-argininosuccinate and/or l-arginine may be transcellularly transported in the nervous system. © 1990.

引用

页码：108 / 112

页数：5

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