THE PARTIAL SEQUENCING OF HUMAN NONSPECIFIC (BONE LIVER KIDNEY) ALKALINE-PHOSPHATASE GENE

被引：3

作者：

HSU, HHT

机构：

[1] Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1991年 / 23卷 / 04期

关键词：

D O I：

10.1016/0020-711X(91)90165-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. A charon 4A human fetal liver genomic library was screened for human nonspecific alkaline phosphatase gene using the cloned human bone cDNA as a hybridization probe. 2. A clone 2.2 Kb DNA was sequenced and found to contain a piece of sequences encoding the 4-44th amino acids of NH2 terminus. 3. The other cloned 1.6 Kb DNA contains two segments of sequences each corresponding to two separate regions of the cDNA for alkaline phosphatase. The first segment of the DNA codes for the 83-141st amino acids whereas the second for 141-199th.

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页码：391 / 393

页数：3

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