N,N',N''-TRIS(3-HYDROXY-6-METHYL-2-PYRIDYLMETHYL)-1,4,7-TRIAZACYCLONANE, A NEW EFFECTIVE LIGAND FOR IRON(III)

被引:40
作者
MARTELL, AE [1 ]
MOTEKAITIS, RJ [1 ]
WELCH, MJ [1 ]
机构
[1] WASHINGTON UNIV,SCH MED,EDWARD MALLINCKRODT INST RADIOL,ST LOUIS,MO 63110
关键词
D O I
10.1039/c39900001748
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A potentiometric pH study of the formation constant of the Fe(III) chelate of N,N',N'-tris(3-hydroxy-6-methyl-2-pyridylmethyl)-1,4,7-triazacyclononane reveals that it is higher than that of any synthetic iron(III) chelate previously reported, and that the ligand binds Fe(III) more strongly at physiological pH than does the microbial siderophore enterobactin.
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页码:1748 / 1749
页数:2
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