INFLUENCE OF ERYTHROCYTE VELOCITY ON IMPEDANCE PLETHYSMOGRAPHIC MEASUREMENTS

Impedance plethysmography has been widely used clinically. However, uncertainty exists concerning the source of the impedance signal. The present study was designed to indicate the relative contributions made by blood volume changes and blood flow changes. An in vitro flow system containing a pulsatile pump, a bovine carotid artery, a rigid tube, and a terminal resis tance was assembled. Impedance recordings were made on both the expansile artery and the rigid tube. The impedance signal from the rigid tube was taken as the flow-related component. The signal from the expansile artery represented the combined effects of volume changes and flow changes. The recordings were made over the full physiological range of pulse pressures and peak flow values, using both normal saline and blood (haematocrit =26±4%). No impedance change was detected in the rigid vessel using saline as the perfusate. When blood was used, the impedance signal from the rigid tube averaged about 10% of that from the expansile vessel and its morphology was different. Changes in erthrocyte velocity produced a small but definite change in the impedance signal recorded from the artery. © 1978 IFMBE.