STUDIES ON CONFORMATION AND REACTIVITY .1. SUGARS WITH POTENTIAL ANTIVIRAL ACTIVITY .4. CONFORMATIONS OF SOME ACYCLIC SUGAR DERIVATIVES

An examination of the conformations adopted by acyclic sugar derivatives has been made. It is shown that 1,3-eclipsed rather than 1,2-gauche interactions are important in determining relative conformer population and that the observed conformer distribution, as determined by analysis of PMR spectra, is close to that calculated from consideration of non-bonded interactions. © 1969.