TAUTOMER-SPECIFIC ANTI-(N-3-SUBSTITUTED)-ADENINE ANTIBODIES - NEW TOOLS IN MOLECULAR DOSIMETRY AND EPIDEMIOLOGY

被引：12

作者：

GLUSENKAMP, KH

KRUGER, K

EBERLE, G

DROSDZIOK, W

JAHDE, E

GRUNDEL, O

NEUHAUS, A

BOESE, R

STELLBERG, P

RAJEWSKY, MF

机构：

[1] ELISABETH HOSP,ESSEN,GERMANY

[2] UNIV GESAMTHSCH ESSEN,INST ANORGAN CHEM,ESSEN,GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 11期

关键词：

D O I：

10.1002/anie.199316401

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

For the determination of individual exposures to alkylating carcinogens, monoclonal antibodies (mabs) that selectively bind a broad spectrum of N3substituted adenines 1 show great potential. The key to the generation of these tautomer‐specific mabs was hapten design based on AM1 calculations. (Figure Presented.) Copyright © 1993 by VCH Verlagsgesellschaft mbH, Germany

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页码：1640 / 1643

页数：4

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