2-METHYLTHIO-LO,11-DIHYDRO-11-(4-METHYL-PIPERAZIN-1-YL)DIBENZO[B,F]THIEPINE MALEIC-ACID (METITEPINE MALEATE)

被引：7

作者：

BLATON, NM

PEETERS, OM

DERANTER, CJ

机构：

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1995年 / 51卷

关键词：

D O I：

10.1107/S0108270194011637

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The crystal structure of metitepine maleate, a mixed 5-HT1/5-HT2 antagonist, has been determined from diffractometer data. The seven-membered ring has a boat-sofa conformation and folds about a line through the S atom and the opposite methylene group. The dihedral angle between the least-squares planes of the aromatic rings is 123.1(1)degrees. The piperazine ring has the normal chair conformation and its mean plane is roughly parallel to the plane of one of the benzene rings.

引用

页码：777 / 780

页数：4

共 23 条

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