SEX-HORMONE CONCENTRATIONS IN MEN WITH ANGIOGRAPHICALLY ASSESSED CORONARY-ARTERY DISEASE - RELATIONSHIP TO OBESITY AND BODY-FAT DISTRIBUTION

被引:28
作者
HAUNER, H
STANGL, K
BURGER, K
BUSCH, U
BLOMER, H
PFEIFFER, EF
机构
[1] UNIV ULM,MED KLIN & POLIKLIN,INNERE MED ABT 1,W-7900 ULM,GERMANY
[2] TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,MED KLIN 1,W-8000 MUNICH 80,GERMANY
来源
KLINISCHE WOCHENSCHRIFT | 1991年 / 69卷 / 14期
关键词
CORONARY ARTERY DISEASE; SEX HORMONES; OBESITY; BODY FAT DISTRIBUTION; ANGIOGRAPHY;
D O I
10.1007/BF01649428
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The relationship between circulating sex hormone levels and the occurrence of coronary artery disease (CAD) was studied in a group of 274 men undergoing coronary angiography. Hormone levels in men with CAD (n = 200) were compared to those in men found to be free of coronary lesions (n = 74). No significant differences were found for serum concentrations of estradiol, total testosterone, sex-hormone-binding globulin, free androgen index, dehydroepiandrosterone sulfate, or cortisol between the two groups. Serum androgens were negatively correlated to age in both groups, whereas estradiol was weakly associated with total cholesterol in the group of men without CAD. No consistent associations were detected between sex hormone levels and the degree of obesity or the distribution of body fat, the latter being assessed by the ratio of waist-to-hip circumferences. The results of this study do not support a significant role of sex steroid hormones in coronary artery disease in men.
引用
收藏
页码:664 / 668
页数:5
相关论文
共 31 条
[1]   OBESITY - NEW INSIGHT INTO THE ANTHROPOMETRIC CLASSIFICATION OF FAT DISTRIBUTION SHOWN BY COMPUTED-TOMOGRAPHY [J].
ASHWELL, M ;
COLE, TJ ;
DIXON, AK .
BRITISH MEDICAL JOURNAL, 1985, 290 (6483) :1692-1694
[2]   POST-HEPARIN LIPASES, LIPIDS AND RELATED HORMONES IN MEN UNDERGOING CORONARY ARTERIOGRAPHY TO ASSESS ATHEROSCLEROSIS [J].
BARTH, JD ;
JANSEN, H ;
HUGENHOLTZ, PG ;
BIRKENHAGER, JC .
ATHEROSCLEROSIS, 1983, 48 (03) :235-241
[3]  
BREIER C, 1985, LANCET, V1, P1242
[4]   INVESTIGATION OF HIRSUTISM - TESTOSTERONE IS NOT ENOUGH [J].
CARTER, GD ;
HOLLAND, SM ;
ALAGHBANDZADEH, J ;
RAYMAN, G ;
DORRINGTONWARD, P ;
WISE, PH .
ANNALS OF CLINICAL BIOCHEMISTRY, 1983, 20 (SEP) :262-263
[5]   SEX-HORMONES AND CORONARY-ARTERY DISEASE [J].
CHUTE, CG ;
BARON, JA ;
PLYMATE, SR ;
KIEL, DP ;
PAVIA, AT ;
LOZNER, EC ;
OKEEFE, T ;
MACDONALD, GJ .
AMERICAN JOURNAL OF MEDICINE, 1987, 83 (05) :853-859
[6]   RELATION BETWEEN PLASMA HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND SEX-HORMONE CONCENTRATIONS IN MEN [J].
DAI, WS ;
GUTAI, JP ;
KULLER, LH ;
LAPORTE, RE ;
FALVOGERARD, L ;
CAGGIULA, A .
AMERICAN JOURNAL OF CARDIOLOGY, 1984, 53 (09) :1259-1283
[7]  
ENTRICAN JH, 1978, LANCET, V2, P487
[8]   THE ASSOCIATION OF RISK-FACTORS WITH ARTERIOGRAPHICALLY DEFINED CORONARY-ARTERY DISEASE - WHAT IS THE APPROPRIATE CONTROL-GROUP [J].
FRIED, LP ;
PEARSON, TA .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1987, 125 (05) :844-853
[9]   SERUM ESTRADIOL AND CORONARY-ARTERY DISEASE [J].
GOLDBERG, RJ ;
GORE, JM ;
ZIVE, M ;
BRADY, P ;
KLAIBER, E ;
BROVERMAN, D ;
OCKENE, IS ;
DALEN, JE .
AMERICAN JOURNAL OF MEDICINE, 1987, 82 (01) :1-4
[10]   PLASMA TESTOSTERONE, HIGH-DENSITY LIPOPROTEIN CHOLESTEROL AND OTHER LIPOPROTEIN FRACTIONS [J].
GUTAI, J ;
LAPORTE, R ;
KULLER, L ;
DAI, W ;
FALVOGERARD, L ;
CAGGIULA, A .
AMERICAN JOURNAL OF CARDIOLOGY, 1981, 48 (05) :897-902