TRISOMY-14 IN HEMATOLOGIC DISEASES - ANOTHER NONRANDOM ABNORMALITY WITHIN MYELOID PROLIFERATIVE DISORDERS

被引：22

作者：

MANCINI, M

CEDRONE, M

NANNI, M

RONDINELLI, MB

PETTI, MC

DECUIA, MR

ALIMENA, G

机构：

[1] Hematology Section, Department of Human Biopathology, University La Sapienza, Rome

来源：

CANCER GENETICS AND CYTOGENETICS | 1993年 / 66卷 / 01期

关键词：

D O I：

10.1016/0165-4608(93)90146-D

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two cases of myelodysplastic syndrome (MDS) and a case of acute nonlymphoblastic leukemia (ANLL) with a trisomy 14 are presented. The series of results derived from our cases, and those previously reported, strongly suggest that this anomaly may be another nonrandom change, confined within myeloid disorders and associated with patients' advanced age, marked tendency to bone marrow dysplastic features, normal platelet values, and not unfavorable prognosis.

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页码：39 / 42

页数：4

相关论文

共 22 条

[1]

DOHNER H, 1990, BLOOD, V76, P1614

[2] EFFECTS OF LOW-DOSES OF RECOMBINANT HUMAN GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF) IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES [J].

ESTEY, EH ;

KURZROCK, R ;

TALPAZ, M ;

MCCREDIE, KB ;

OBRIEN, S ;

KANTARJIAN, HM ;

KEATING, MJ ;

DEISSEROTH, AB ;

GUTTERMAN, JU .

BRITISH JOURNAL OF HAEMATOLOGY, 1991, 77 (03) :291-295

[3] TRISOMY-14 IN REFRACTORY-ANEMIA WITH EXCESS OF BLASTS IN TRANSFORMATION [J].

HAAS, OA ;

JAGER, U ;

AMBROS, P ;

PABINGER, I .

CANCER GENETICS AND CYTOGENETICS, 1987, 29 (02) :315-318

[4] NUMERICAL CHROMOSOME-ABERRATIONS IN HUMAN NEOPLASIA [J].

HEIM, S ;

MITELMAN, F .

CANCER GENETICS AND CYTOGENETICS, 1986, 22 (02) :99-108

[5] CYTOGENETIC ANALYSIS OF 54 CASES OF MYELODYSPLASTIC SYNDROME [J].

JOTTERANDBELLOMO, M ;

PARLIER, V ;

SCHMIDT, PM ;

BERIS, P .

CANCER GENETICS AND CYTOGENETICS, 1990, 46 (02) :157-172

[6]

LI YS, 1983, SCAND J HAEMATOL, V30, P265

[7]

LI YS, 1984, LEUKEMIA RES, V8, P699

[8] LEUKEMIA OF LARGE GRANULAR LYMPHOCYTES - ASSOCIATION WITH CLONAL CHROMOSOMAL-ABNORMALITIES AND AUTOIMMUNE NEUTROPENIA, THROMBOCYTOPENIA, AND HEMOLYTIC-ANEMIA [J].

LOUGHRAN, TP ;

KADIN, ME ;

STARKEBAUM, G ;

ABKOWITZ, JL ;

CLARK, EA ;

DISTECHE, C ;

LUM, LG ;

SLICHTER, SJ .

ANNALS OF INTERNAL MEDICINE, 1985, 102 (02) :169-175

[9] MULTIPLE CHROMOSOMALLY DISTINCT CELL-POPULATIONS IN MYELODYSPLASTIC SYNDROMES AND THEIR POSSIBLE SIGNIFICANCE IN THE EVOLUTION OF THE DISEASE [J].

MECUCCI, C ;

REGECAMBRIN, G ;

MICHAUX, JL ;

TRICOT, G ;

VANDENBERGHE, H .

BRITISH JOURNAL OF HAEMATOLOGY, 1986, 64 (04) :699-706

[10] TRISOMY-14 - A NEW ENTITY WITHIN ACUTE NONLYMPHOCYTIC LEUKEMIA [J].

MELONIBALLIET, A ;

MORGAN, R ;

POTH, JL ;

KINGSLEY, EC ;

SANDBERG, AA .

CANCER GENETICS AND CYTOGENETICS, 1989, 43 (01) :35-38