EFFECT OF SOMETRIBOVE ADMINISTRATION ON LH CONCENTRATION IN DAIRY-CATTLE

被引:10
作者
DALTON, JC [1 ]
MARCINKOWSKI, DP [1 ]
机构
[1] UTAH STATE UNIV,DEPT ANIM DAIRY & VET SCI,LOGAN,UT 84322
关键词
SOMATOTROPIN; LUTEINIZING HORMONE; PROGESTERONE; DAIRY CATTLE;
D O I
10.1016/0093-691X(94)90079-X
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sixteen lactating, normally cycling Holstein cows were used to study 1) the effects of sometribove (recombinant methionyl bST) administration on basal LH concentrations and 2) the pituitary response to a GnRH challenge during the breeding period. The cows received a 3-injection regimen of PGF2 alpha for estrus synchronization between 40 and 50 d post partum, and were assigned to a control group or to sometribove treatment (25 mg/d), which began 54 to 59 d post partum. Duration of the bST treatment was 24 d. On Day 10 of the estrous cycle following the third PGF2 alpha injection, blood samples were collected to determine basal concentrations of LH. Immediately following this collection period, a GnRH challenge (100 mu g) was used to measure the responsiveness of the pituitary based on the subsequent LH peak. Milk production of sometribove-treated cows increased 7% (2.1 kg/d) above that of the controls. Sometribove did not affect basal or GnRH-induced LH concentrations. Plasma progesterone concentrations during the luteal phase were similar between treatments. Sometribove increased milk yield with no apparent effects on basal or GnRH-induced LH concentrations during the breeding period.
引用
收藏
页码:437 / 445
页数:9
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