HORMONAL STIMULATION OF LACTOSE SYNTHETASE IN MAMMARY CARCINOMA

被引：31

作者：

MCGUIRE, WL

机构：

[1] Endocrinology Branch, National Cancer Institute, Bethesda

[2] University of Texas Medical School, San Antonio, TX 78229

来源：

SCIENCE | 1969年 / 165卷 / 3897期

关键词：

D O I：

10.1126/science.165.3897.1013

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A transplantable rat mammary carcinoma (R3230AC) synthesizes significant quantities of the mammary gland enzyme lactose synthetase in the immature virgin female rat. In this hormonal environment, mammary glands do not synthesize the enzyme. Prolactin further stimulates the enzyme activity in the tumors to levels found only in mammary glands of rats in late pregnancy or during lactation.

引用

页码：1013 / +

页数：1

共 8 条

[1] MECHANISM OF INDUCTION OF MAMMARY DIFFERENTIATION IN SPRAGUE-DAWLEY FEMALE RATS BY PERPHENAZINE [J].