FORMATION AND STABILIZATION OF PERFLUOROCARBON EMULSIONS

被引：19

作者：

MAGDASSI, S

SIMANTOV, A

机构：

[1] Casali Institute of Applied Chemistry, School of Applied Science and Technology, The Hebrew University of Jerusalem

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1990年 / 59卷 / 01期

关键词：

Emulsion; Lecithin; Perfluorocarbon; Zeta potential;

D O I：

10.1016/0378-5173(90)90065-C

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The formation and stabilization of perfluorocarbon emulsions with pluronic F-68 and soya lecithin were investigated. Greater ease of formation and stability were achieved with the soya lecithin. It was found that, in general, smaller droplet size was obtained with the emulsions prepared with lecithin, at all dispersed phase fractions. Zeta potential measurements indicated that the emulsions are stabilized via an electrostatic mechanism; the zeta potential increased with increasing lecithin concentration, up to a constant high value, and decreased with increasing dispersed phase fraction. © 1990.

引用

页码：69 / 72

页数：4

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