COMPARISON OF IMPEDANCE AT THE MICROELECTRODE SALINE AND MICROELECTRODE CULTURE-MEDIUM INTERFACE

被引：8

作者：

CARTER, SJ ^{[1
]}

LINKER, CJ ^{[1
]}

TURKLEHUSLIG, T ^{[1
]}

HOWARD, LL ^{[1
]}

机构：

[1] SO METHODIST UNIV,SCH ENGN & APPL SCI,DALLAS,TX 75275

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 1992年 / 39卷 / 11期

关键词：

D O I：

10.1109/10.168691

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The impedance characteristics of gold-plated indium-tin-oxide microelectrodes immersed in culture medium (MEM) are described and compared with the impedance characteristics observed when those microelectrodes are immersed in isotonic saline. For microelectrode areas of approximately 100 mum2, applied voltage levels of 5, 50, and 100 mV, and for frequencies of from 100 Hz to 10 kHz the resistance, capacitance, capacitive reactance, and total impedance are given as a function of frequency both in culture medium and in saline. The results, which hold for current densities ranging from 0.45 to 700 pA/mum2, are compared. Also given are the alpha and K values determining the frequency characteristics of the interface resistance and capacitance in medium and in saline.

引用

页码：1123 / 1129

页数：7

共 8 条

[1]

DROGE MH, 1986, J NEUROSCI, V6, P1583

[2]

Fricke H, 1932, PHILOS MAGAZINE J SC, V14, P310

[3]

Geddes L. A., 1972, ELECTRODES MEASUREME

[4] TRANSPARENT INDIUM TIN OXIDE ELECTRODE PATTERNS FOR EXTRACELLULAR, MULTISITE RECORDING IN NEURONAL CULTURES [J].