ENANTIOSELECTIVE HYDROLYSIS OF 2,2-DISUBSTITUTED OXIRANES MEDIATED BY MICROSOMAL EPOXIDE HYDROLASE

被引：3

作者：

BASAVAIAH, D

RAJU, SB

机构：

[1] School of Chemistry, University of Hyderabad

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 21期

关键词：

D O I：

10.1080/00397919508013848

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Aryl-2-methyloxiranes are enantioselectively hydrolyzed with microsomal epoxide hydrolase from pig liver to provide 1,2-diols containing a tertiary benzylic alcohol stereogenic centre upto 34% enantiomeric purities.

引用

页码：3293 / 3306

页数：14

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