COMPLETE REMISSION OF BRAIN METASTASES OF OVARIAN-CANCER FOLLOWING HIGH-DOSE CARBOPLATIN - A CASE-REPORT AND PHARMACOKINETIC STUDY

被引：30

作者：

VLASVELD, LT ^{[1
]}

BEYNEN, JH ^{[1
]}

BOOGERD, W ^{[1
]}

HUININK, WWT ^{[1
]}

RODENHUIS, S ^{[1
]}

机构：

[1] NETHERLANDS CANC INST,DEPT NEUROL,1066 CX AMSTERDAM,NETHERLANDS

来源：

CANCER CHEMOTHERAPY AND PHARMACOLOGY | 1990年 / 25卷 / 05期

关键词：

D O I：

10.1007/BF00686244

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Brain metastases developed in a 40-year-old woman with relapsed ovarian cancer 2 years after cisplatin-based combination chemotherapy. After a single dose of 800 mg/m2 carboplatin, complete remission of the brain metastases occurred. A pharmacokinetic study during the second course revealed low levels of carboplatin in the cerebrospinal fluid. © 1990 Springer-Verlag.

引用

页码：382 / 383

页数：2

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