ENKEPHALINS INCREASE DOPAMINE LEVELS IN THE CNS OF A MARINE MOLLUSK

被引：68

作者：

STEFANO, GB

CATAPANE, EJ

机构：

[1] CUNY,MEDGAR EVERS COLL,DEPT NAT SCI,BROOKLYN,NY

[2] E COAST NEUROSCI FDN,BROOKLYN,NY

来源：

LIFE SCIENCES | 1979年 / 24卷 / 17期

关键词：

D O I：

10.1016/0024-3205(79)90024-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Intracardiac administration of methionine enkephalin and leucine enkephalin increased dopamine but not serotonin levels in the CNS of the marine mollusc Mytilus edulis. Naloxone blocked the effects of the enkephalins. These responses displayed a time dependent desensitization to methionine enkephalin. The study suggests the presence of an opiate receptor mechanism in this invertebrate species. © 1979.

引用

页码：1617 / 1621

页数：5

共 16 条

[1] ANALGESIA INDUCED INVIVO BY CENTRAL ADMINISTRATION OF ENKEPHALIN IN RAT
BELLUZZI, JD
GRANT, N
GARSKY, V
SARANTAKIS, D
WISE, CD
STEIN, L
[J]. NATURE, 1976, 260 (5552) : 625 - 626
[2] STIMULATION OF DOPAMINE SYNTHESIS IN CAUDATE-NUCLEUS BY INTRASTRIATAL ENKEPHALINS AND ANTAGONISM BY NALOXONE
BIGGIO, G
CASU, M
CORDA, MG
DIBELLO, C
GESSA, GL
[J]. SCIENCE, 1978, 200 (4341) : 552 - 554
[3] FRONTALI N, 1977, PEPTIDES NEUROBIOLOG, P259
[4] HILLER JM, 1973, RES COMMUN CHEM PATH, V6, P1052
[5] ISOLATION OF AN ENDOGENOUS COMPOUND FROM BRAIN WITH PHARMACOLOGICAL PROPERTIES SIMILAR TO MORPHINE
HUGHES, J
[J]. BRAIN RESEARCH, 1975, 88 (02) : 295 - 308
[6] IFDHIN MS, 1975, NATURE, V254, P72
[7] REGIONAL DISTRIBUTION OF OPIATE RECEPTOR BINDING IN MONKEY AND HUMAN BRAIN
KUHAR, MJ
PERT, CB
SNYDER, SH
[J]. NATURE, 1973, 245 (5426) : 447 - 450
[8] PHYLOGENETIC DISTRIBUTION OF OPIATE RECEPTOR-BINDING
PERT, CB
APOSHIAN, D
SNYDER, SH
[J]. BRAIN RESEARCH, 1974, 75 (02) : 356 - 361
[9] DOPAMINERGIC AGENTS - INFLUENCE ON SEROTONIN IN MOLLUSCAN NERVOUS-SYSTEM
STEFANO, GB
CATAPANE, E
AIELLO, E
[J]. SCIENCE, 1976, 194 (4264) : 539 - 541
[10] SEASONAL MONOAMINE CHANGES IN CENTRAL NERVOUS-SYSTEM OF MYTILUS-EDULIS (BIVALVIA)
STEFANO, GB
CATAPANE, EJ
[J]. EXPERIENTIA, 1977, 33 (10): : 1341 - 1342

← 1 2 →